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Friday, 19 January 2024 11:40

Dr. Vesna Martinović

Physiology and molecular biology of plants studies the mechanisms underlying plant growth and development, plant morphogenesis in vitro (organogenesis, somatic embryogenesis, androgenesis), synthesis and accumulation of specialised metabolites, plant responses to different types of stressors, as well as allelopathic relationships between plants.

Inflammation is a response to damage and danger in organisms and is an integral part of research in immunology, but also in other scientific disciplines, since inflammation occurs in numerous pathological conditions like diabetes or cancer. Immunology studies body’s defence mechanisms at cellular and molecular level in infective diseases, as well as immune system malfunctions in autoimmune diseases and allergies Modification of body’s immune system is useful in treatment of these diseases, and can be performed through pharmacological modulation or immunotherapy, where immune cells or their parts are used. Acute-phase proteins and potential biological markers of inflammation involved in the modification and integration of signalling pathways are being investigated in order to predict and intervene in diseases.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Friday, 19 January 2024 11:40

Dr. Svetlana Dinić

EDUCATION
2006 - PhD in Biological Sciences, Faculty of Biology (FB), University of Belgrade (UB)
2000 - MSc in Biological Sciences, FB, UB
1997 - BSc in Molecular Biology and Physiology, FB, UB

RESEARCH EXPERIENCE
2017 - Principal Research Fellow, Department of Molecular Biology (DMB), IBISS, UB
2012 - 2017 - Senior Research Associate, DMB, IBISS, UB
2007 - 2012 - Research Associate, DMB, IBISS, UB
2001 - 2007 - Research Assistant, DMB, IBISS, UB
1998 - 2000 - Scholarship, Ministry of Science and Technology, Republic of Serbia (RS)

RESEARCH INTEREST
Natural substances as potential supplements/therapeutics for the prevention and treatment of diabetes and its complications; Epigenetic regulation of gene expression and targeted methylation of particular gene loci - mechanisms of DNA methylation/demethylation and their functional relationship to altered signaling pathways in diabetes and cancer pathogenesis; Nutriepigenetics and nutriepigenomics.

PROJECTS
National:
2020- IBISS work program (No. 451-03-66/2024-03/200007), Ministry of Education, Technological Development and Innovation, RS
2011 - 2019 - OI173020, Ministry of Research and Technological Development, RS
2006 - 2010 - #143002B, Ministry of Science and Environmental Protection, RS
2002 - 2006 - #1722, Ministry of Science, Technology and Development, RS
International:
2024 - 2027 - Project: Strengthening Translational Research for Improved Metabolic Health (STRIMHealth) (Twining call HORIZON-WIDERA-2023, HORIZON EUROPE, European Commission)
2014 - 2019 - Project: Managing the effects of multiple stressors on aquatic ecosystems under water scarcity (Globaqua) (European Commission 7th Framework Programme Funding; No. 603629-ENV-2013-6.2.1)
2011 - 2024 - Participant in 5 COST Actions (TD0905, FA1201, CA16112 (MC member), CA15219 (MC substitute), CA21113).

SCIENTIFIC SOCIETIES
- Serbian Society for Molecular Biology - Vice president of the Governing Board
- Serbian Biochemical Society - member of the Advanced Courses Committee
- Serbian Proteomic Association - member of Governing Board (2015 - 2019); founding Council
- Serbian Biological Society

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.

Nutrition is the process by which the body uses food to produce energy and sustain life. The science of nutrition studies the role of nutrients and other food components in the growth, reproduction, health and disease of the organism. Food ingredients with medicinal properties are called nutriceuticals and can be used to treat or prevent disease. There are more and more alternative sources of food, such as edible insects, which should limit the negative impact of food production on the environment.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Natural products are complex chemical compounds synthesised by living organisms through biochemical processes, with a specific physiological or ecological function. Researchers at the Institute study the chemical characterization and isolation of natural products, metabolic engineering, as well as the assessment of the possibility of their application in industry (as medicaments, dietary supplements and functional food, biopesticides).

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Friday, 19 January 2024 11:40

Dr. Nevena Grdović

Education:
• 1998 B.Sc., Faculty of Biology, University of Belgrade, Department of Molecular Biology and Physiology: Average grade: 9.36/10
• 2002 M.Sc., Faculty of Biology, University of Belgrade
• 2007 Ph.D., Faculty of Biology, University of Belgrade

Research title:
• 2002: Research Assistant
• 2008: Research Associate
• 2013: Senior Research Associate
• 2020: Principal Research Fellow

Research interest:
• Diabetes (T1D and T2D) including pathophysiological mechanisms underlying the onset of diabetes and diabetic complications; Epigenetic changes, especially changes in DNA methylation/demethylation and their impact on the expression of genes relevant for the development of diabetes, fibroproliferative diseases and cancer. Novel research is directed towards targeted methylation of certain gene loci with the aim of changing the phenotype of cells.

Participation in projects:
National projects: The IBISS work program financed by the Ministry of Education, Technological Development and Innovation, Republic of Serbia (2020-), contract number 451-03-66/2024-03/ 200007; OI173020 of the Ministry of Research and Technological Development, Republic of Serbia (2011 - 2019); #143002B of the Ministry of Science and Environmental Protection, Republic of Serbia (2006 - 2010); #1722 of the Ministry of Science, Technology and Development, Republic of Serbia (2002 – 2006).
International projects and collaborations: Project of 7th Framework Programme of European Commission „Managing the effects of multiple stressors on aquatic ecosystems under water scarcity“ No. 603629-ENV-2013-6.2.1-Globaqua (2014 - 2019); Participation and coordination of international cooperation with Dr. Ludwig Wagner, Medical University of Vienna, Austria; dr. Talin Barisani-Asenbauer, Center for Pathophysiology, Infectiology & Immunology, Vienna, Austria; dr. Tomasz Jurkowski, Institute for Biochemistry, University of Stuttgart, Germany; COST actions: TD0905 (2010-2014), CA15219 (2016-2020), CA16119 (2017-2021).

Memberships in scientific societies:
• Serbian Society for Molecular Biology
• Serbian Biochemical Society – Member of the Fellowships Committee (2014 – 2017); Member of the Scientific Committee for the Serbian Biochemical Society Conferences (III – VII)
• Serbian Proteomic Association (SePA)
• Serbian Biological Society

Understanding the physiological and functional characteristics of cancer cells at the individual level, and the tumor tissue as a highly orchestrated multicellular formation, by whose activity the tumor expands, invades and disseminates, is the main goal of cancer biology research today. Defining the causes of abnormal behavior of neoplastic cells individually and in the context of the tumor microenvironment, including the histological, metabolic and immunological specificities of this tissue, represents a platform for designing new approaches in cancer treatment. Investigating the phenomenon of initial or acquired tumor resistance helps to gain deeper insights into the reasons for limited effects of the conventional treatments, enabling the improvement of existing protocols.

Ecotoxicology studeies the toxic effects of chemicals on the environment. The effects are studied at the level of molecules, cells, tissues, organs, individual organisms, populations or ecosystems.

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.

Nutrition is the process by which the body uses food to produce energy and sustain life. The science of nutrition studies the role of nutrients and other food components in the growth, reproduction, health and disease of the organism. Food ingredients with medicinal properties are called nutriceuticals and can be used to treat or prevent disease. There are more and more alternative sources of food, such as edible insects, which should limit the negative impact of food production on the environment.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Natural products are complex chemical compounds synthesised by living organisms through biochemical processes, with a specific physiological or ecological function. Researchers at the Institute study the chemical characterization and isolation of natural products, metabolic engineering, as well as the assessment of the possibility of their application in industry (as medicaments, dietary supplements and functional food, biopesticides).

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Friday, 19 January 2024 11:40

Dr. Mirjana Mihailović

Graduated in 1996; she received her master's degree in 1998 and her doctorate in 2004 at the Faculty of Biology at the University of Belgrade. After graduation, she was hired as a scholarship holder of the Ministry of Science at the Department of Molecular Biology of the Institute for Biological Research "Siniša Stanković", and since 1998 she has been employed in the same department. Scientific advisor of the Institute for Biological Research "Siniša Stanković" since 2011.

Signaling molecules and molecular mechanisms that control the regeneration of beta-cells of the pancreas and new approaches in preventing beta-cell dysfunction; The interaction of genetic and epigenetic factors in the altered signaling pathways in diabetes; Oxidative stress and inflammation in the pathogenesis and progression of diabetes and diabetes related complications; Molecular mechanisms of actions of the natural substances (plant extrcats, mushrooms, probiotics) and dietary supplements as potential therapeutic agents in order to prevent the destruction of pancreatic β-cells and the progression of diabetes; Biomonitoring-the role of biomarkers in assessing the degree of contamination of aquatic organisms in the presence of xenobiotics.

Memberships in scientific societies:
Serbian Biological Society
Serbian Society for Molecular Biology
Serbian Biochemical Society
Serbian Association for Proteomics

Participation in 16 national and international projects and calls.

Since 2007, she has been engaged as a lecturer in the doctoral studies of "Molecular Biology" (subjects: Proteomics and Epigenetics) which are supported by the Faculty of Biology in Belgrade, the Institute for Biological Research "Siniša Stanković" and the Institute for Molecular Biology and Genetic Engineering

Commentator and/or member of the commission for the defense of 7 doctoral dissertations, 1 master's and 2 diploma theses.
Reviewer in over 30 international and national journal, as well as international projects.

Biomonitoring is the process of systematically observing, measuring, and analysing the physiological, biochemical, molecular, and genetic responses of living organisms to environmental changes, thus providing qualitative or quantitative information on the state of the environment. It includes the use of various bioindicators, biomonitors, bioaccumulators, and biomarkers.

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.

Animal physiology studies how biological processes work, how they operate under different environmental conditions, and how these processes are regulated and integrated. They can be studied at different levels of organisation, from organelles and cell membranes to cells, tissues, organ systems, and the whole animal, both during development and in adulthood.

Inflammation is a response to damage and danger in organisms and is an integral part of research in immunology, but also in other scientific disciplines, since inflammation occurs in numerous pathological conditions like diabetes or cancer. Immunology studies body’s defence mechanisms at cellular and molecular level in infective diseases, as well as immune system malfunctions in autoimmune diseases and allergies Modification of body’s immune system is useful in treatment of these diseases, and can be performed through pharmacological modulation or immunotherapy, where immune cells or their parts are used. Acute-phase proteins and potential biological markers of inflammation involved in the modification and integration of signalling pathways are being investigated in order to predict and intervene in diseases.

Nutrition is the process by which the body uses food to produce energy and sustain life. The science of nutrition studies the role of nutrients and other food components in the growth, reproduction, health and disease of the organism. Food ingredients with medicinal properties are called nutriceuticals and can be used to treat or prevent disease. There are more and more alternative sources of food, such as edible insects, which should limit the negative impact of food production on the environment.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Natural products are complex chemical compounds synthesised by living organisms through biochemical processes, with a specific physiological or ecological function. Researchers at the Institute study the chemical characterization and isolation of natural products, metabolic engineering, as well as the assessment of the possibility of their application in industry (as medicaments, dietary supplements and functional food, biopesticides).

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Friday, 10 November 2023 10:20

The 5th B Chromosome Conference

The 5th B Chromosome Conference was held in Petnica, October 14-17 2023, organized by the Institute for Biological Research "Siniša Stanković" and the Serbia Genetic Society as co-organizers. Eight plenary lectures, eighteen oral and seven poster presentations were held.

Biomonitoring is the process of systematically observing, measuring, and analysing the physiological, biochemical, molecular, and genetic responses of living organisms to environmental changes, thus providing qualitative or quantitative information on the state of the environment. It includes the use of various bioindicators, biomonitors, bioaccumulators, and biomarkers.

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.

Animal physiology studies how biological processes work, how they operate under different environmental conditions, and how these processes are regulated and integrated. They can be studied at different levels of organisation, from organelles and cell membranes to cells, tissues, organ systems, and the whole animal, both during development and in adulthood.

Inflammation is a response to damage and danger in organisms and is an integral part of research in immunology, but also in other scientific disciplines, since inflammation occurs in numerous pathological conditions like diabetes or cancer. Immunology studies body’s defence mechanisms at cellular and molecular level in infective diseases, as well as immune system malfunctions in autoimmune diseases and allergies Modification of body’s immune system is useful in treatment of these diseases, and can be performed through pharmacological modulation or immunotherapy, where immune cells or their parts are used. Acute-phase proteins and potential biological markers of inflammation involved in the modification and integration of signalling pathways are being investigated in order to predict and intervene in diseases.

Nutrition is the process by which the body uses food to produce energy and sustain life. The science of nutrition studies the role of nutrients and other food components in the growth, reproduction, health and disease of the organism. Food ingredients with medicinal properties are called nutriceuticals and can be used to treat or prevent disease. There are more and more alternative sources of food, such as edible insects, which should limit the negative impact of food production on the environment.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Natural products are complex chemical compounds synthesised by living organisms through biochemical processes, with a specific physiological or ecological function. Researchers at the Institute study the chemical characterization and isolation of natural products, metabolic engineering, as well as the assessment of the possibility of their application in industry (as medicaments, dietary supplements and functional food, biopesticides).

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Lecturer: Dr. Ivan Milenković, Oldenburg University

Time: Tuesday, 14th November 2023, 12.00

Venue: IBISS Library

Biomonitoring is the process of systematically observing, measuring, and analysing the physiological, biochemical, molecular, and genetic responses of living organisms to environmental changes, thus providing qualitative or quantitative information on the state of the environment. It includes the use of various bioindicators, biomonitors, bioaccumulators, and biomarkers.

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.

Animal physiology studies how biological processes work, how they operate under different environmental conditions, and how these processes are regulated and integrated. They can be studied at different levels of organisation, from organelles and cell membranes to cells, tissues, organ systems, and the whole animal, both during development and in adulthood.

Inflammation is a response to damage and danger in organisms and is an integral part of research in immunology, but also in other scientific disciplines, since inflammation occurs in numerous pathological conditions like diabetes or cancer. Immunology studies body’s defence mechanisms at cellular and molecular level in infective diseases, as well as immune system malfunctions in autoimmune diseases and allergies Modification of body’s immune system is useful in treatment of these diseases, and can be performed through pharmacological modulation or immunotherapy, where immune cells or their parts are used. Acute-phase proteins and potential biological markers of inflammation involved in the modification and integration of signalling pathways are being investigated in order to predict and intervene in diseases.

Nutrition is the process by which the body uses food to produce energy and sustain life. The science of nutrition studies the role of nutrients and other food components in the growth, reproduction, health and disease of the organism. Food ingredients with medicinal properties are called nutriceuticals and can be used to treat or prevent disease. There are more and more alternative sources of food, such as edible insects, which should limit the negative impact of food production on the environment.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Natural products are complex chemical compounds synthesised by living organisms through biochemical processes, with a specific physiological or ecological function. Researchers at the Institute study the chemical characterization and isolation of natural products, metabolic engineering, as well as the assessment of the possibility of their application in industry (as medicaments, dietary supplements and functional food, biopesticides).

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

At this year's competition "Communities Together" announced by the NIS company, IBISS won funds in the amount of 1,107,852.00 dinars, which are intended for the purchase of an automated biochemical analyzer. The procurement, installation and commissioning of the analyzer will take place over the next few months.

Biomonitoring is the process of systematically observing, measuring, and analysing the physiological, biochemical, molecular, and genetic responses of living organisms to environmental changes, thus providing qualitative or quantitative information on the state of the environment. It includes the use of various bioindicators, biomonitors, bioaccumulators, and biomarkers.

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.

Animal physiology studies how biological processes work, how they operate under different environmental conditions, and how these processes are regulated and integrated. They can be studied at different levels of organisation, from organelles and cell membranes to cells, tissues, organ systems, and the whole animal, both during development and in adulthood.

Inflammation is a response to damage and danger in organisms and is an integral part of research in immunology, but also in other scientific disciplines, since inflammation occurs in numerous pathological conditions like diabetes or cancer. Immunology studies body’s defence mechanisms at cellular and molecular level in infective diseases, as well as immune system malfunctions in autoimmune diseases and allergies Modification of body’s immune system is useful in treatment of these diseases, and can be performed through pharmacological modulation or immunotherapy, where immune cells or their parts are used. Acute-phase proteins and potential biological markers of inflammation involved in the modification and integration of signalling pathways are being investigated in order to predict and intervene in diseases.

Nutrition is the process by which the body uses food to produce energy and sustain life. The science of nutrition studies the role of nutrients and other food components in the growth, reproduction, health and disease of the organism. Food ingredients with medicinal properties are called nutriceuticals and can be used to treat or prevent disease. There are more and more alternative sources of food, such as edible insects, which should limit the negative impact of food production on the environment.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Natural products are complex chemical compounds synthesised by living organisms through biochemical processes, with a specific physiological or ecological function. Researchers at the Institute study the chemical characterization and isolation of natural products, metabolic engineering, as well as the assessment of the possibility of their application in industry (as medicaments, dietary supplements and functional food, biopesticides).

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Tuesday, 31 October 2023 12:23

Stanford's list for 2022 has been published

A group of researchers at Stanford University has updated the author database of standardised citation indicators and published the results for 2022. This list includes the most cited scientists from across academia and this year also includes our three colleagues, researchers from the Institute of Biological Research "Siniša Stanković", Dr. Marina Soković, Dr. Jasmina Glamočlija and Dr. Marija Ivanov, associates of the Department of Plant Physiology.

Biomonitoring is the process of systematically observing, measuring, and analysing the physiological, biochemical, molecular, and genetic responses of living organisms to environmental changes, thus providing qualitative or quantitative information on the state of the environment. It includes the use of various bioindicators, biomonitors, bioaccumulators, and biomarkers.

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.

Animal physiology studies how biological processes work, how they operate under different environmental conditions, and how these processes are regulated and integrated. They can be studied at different levels of organisation, from organelles and cell membranes to cells, tissues, organ systems, and the whole animal, both during development and in adulthood.

Inflammation is a response to damage and danger in organisms and is an integral part of research in immunology, but also in other scientific disciplines, since inflammation occurs in numerous pathological conditions like diabetes or cancer. Immunology studies body’s defence mechanisms at cellular and molecular level in infective diseases, as well as immune system malfunctions in autoimmune diseases and allergies Modification of body’s immune system is useful in treatment of these diseases, and can be performed through pharmacological modulation or immunotherapy, where immune cells or their parts are used. Acute-phase proteins and potential biological markers of inflammation involved in the modification and integration of signalling pathways are being investigated in order to predict and intervene in diseases.

Nutrition is the process by which the body uses food to produce energy and sustain life. The science of nutrition studies the role of nutrients and other food components in the growth, reproduction, health and disease of the organism. Food ingredients with medicinal properties are called nutriceuticals and can be used to treat or prevent disease. There are more and more alternative sources of food, such as edible insects, which should limit the negative impact of food production on the environment.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Natural products are complex chemical compounds synthesised by living organisms through biochemical processes, with a specific physiological or ecological function. Researchers at the Institute study the chemical characterization and isolation of natural products, metabolic engineering, as well as the assessment of the possibility of their application in industry (as medicaments, dietary supplements and functional food, biopesticides).

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Dr. Marijana Skorić from the Department of Plant Physiology on behalf of IBISS participated at „The Second China-CEEC Conference on Technology Cooperation and Exchange“ in Nanjing, October 18-23, 2023.

Biomonitoring is the process of systematically observing, measuring, and analysing the physiological, biochemical, molecular, and genetic responses of living organisms to environmental changes, thus providing qualitative or quantitative information on the state of the environment. It includes the use of various bioindicators, biomonitors, bioaccumulators, and biomarkers.

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.

Animal physiology studies how biological processes work, how they operate under different environmental conditions, and how these processes are regulated and integrated. They can be studied at different levels of organisation, from organelles and cell membranes to cells, tissues, organ systems, and the whole animal, both during development and in adulthood.

Inflammation is a response to damage and danger in organisms and is an integral part of research in immunology, but also in other scientific disciplines, since inflammation occurs in numerous pathological conditions like diabetes or cancer. Immunology studies body’s defence mechanisms at cellular and molecular level in infective diseases, as well as immune system malfunctions in autoimmune diseases and allergies Modification of body’s immune system is useful in treatment of these diseases, and can be performed through pharmacological modulation or immunotherapy, where immune cells or their parts are used. Acute-phase proteins and potential biological markers of inflammation involved in the modification and integration of signalling pathways are being investigated in order to predict and intervene in diseases.

Nutrition is the process by which the body uses food to produce energy and sustain life. The science of nutrition studies the role of nutrients and other food components in the growth, reproduction, health and disease of the organism. Food ingredients with medicinal properties are called nutriceuticals and can be used to treat or prevent disease. There are more and more alternative sources of food, such as edible insects, which should limit the negative impact of food production on the environment.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Natural products are complex chemical compounds synthesised by living organisms through biochemical processes, with a specific physiological or ecological function. Researchers at the Institute study the chemical characterization and isolation of natural products, metabolic engineering, as well as the assessment of the possibility of their application in industry (as medicaments, dietary supplements and functional food, biopesticides).

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Lecturer: Dr. Markus Schosserer

Time: Wednesday, 15th November 2023, 13.00

Venue: IBISS Library

Biomonitoring is the process of systematically observing, measuring, and analysing the physiological, biochemical, molecular, and genetic responses of living organisms to environmental changes, thus providing qualitative or quantitative information on the state of the environment. It includes the use of various bioindicators, biomonitors, bioaccumulators, and biomarkers.

Epigenetics studies changes in gene expression that are not accompanied by changes in the sequence of DNA molecules, as well as their transmission and transgenerational maintenance. Researchers at the Institute study the mechanisms of stable maintenance of expression of certain genes (mechanisms of changes in the DNA methylation pattern), as well as the possibility of changing epigenetic marks for therapeutic purposes using CRISPR/Cas9 fused constructs. The target diseases researchers are focused on are diabetes and triple negative breast cancer.

Animal physiology studies how biological processes work, how they operate under different environmental conditions, and how these processes are regulated and integrated. They can be studied at different levels of organisation, from organelles and cell membranes to cells, tissues, organ systems, and the whole animal, both during development and in adulthood.

Inflammation is a response to damage and danger in organisms and is an integral part of research in immunology, but also in other scientific disciplines, since inflammation occurs in numerous pathological conditions like diabetes or cancer. Immunology studies body’s defence mechanisms at cellular and molecular level in infective diseases, as well as immune system malfunctions in autoimmune diseases and allergies Modification of body’s immune system is useful in treatment of these diseases, and can be performed through pharmacological modulation or immunotherapy, where immune cells or their parts are used. Acute-phase proteins and potential biological markers of inflammation involved in the modification and integration of signalling pathways are being investigated in order to predict and intervene in diseases.

Nutrition is the process by which the body uses food to produce energy and sustain life. The science of nutrition studies the role of nutrients and other food components in the growth, reproduction, health and disease of the organism. Food ingredients with medicinal properties are called nutriceuticals and can be used to treat or prevent disease. There are more and more alternative sources of food, such as edible insects, which should limit the negative impact of food production on the environment.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Natural products are complex chemical compounds synthesised by living organisms through biochemical processes, with a specific physiological or ecological function. Researchers at the Institute study the chemical characterization and isolation of natural products, metabolic engineering, as well as the assessment of the possibility of their application in industry (as medicaments, dietary supplements and functional food, biopesticides).

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

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