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On Wednesday, March 12, 2025, the conference "Scientific research projects tailored to business - experiences and opportunities in the pharmaceutical industry" was held at the Serbian Chamber of Commerce. During the meeting, Dr. Ana Đorđević presented the potential of IBISS for cooperation with the pharmaceutical industry, as well as the ongoing collaborative UTRL project "LiverDophilus - Probiotic bacteria for the treatment of liver steatosis", which is funded through SAIGE and realized through the cooperation between IBISS, IMGGI and the pharmaceutical company Phytonet.

On March 11-12, 2025, the Institute for Biological Research “Siniša Stanković” hosted an intensive hands-on training session focused on mass spectrometry data processing in lipidomics. This training was a sort of continuation and deepening of the Training in Analytical Methods for Mass Spectrometry-based Lipidomics held in October of the previous year, aimed at engaging participants more actively with real research datasets.

The first training on EU research funding and project management, organized as part of the STRIMHealth project, has been successfully completed. Held at IBISS on March 10th, Belgrade, the training covered key topics on funding opportunities and the grant preparation process.

Thursday, 27 February 2025 11:07

Workshop on Research Data Management

As part of the STRIMHealth project activities aimed at enhancing project proposal writing and the implementation of EU-funded projects, we are pleased to announce the Workshop on Research Data Management (RDM). The workshop will be held online on March 17–18, 2025.

Wednesday, 19 February 2025 15:41

Marija Pinjić

Marija Pinjić completed her B.Sc. in 2022 at the Faculty of Biology, University of Belgrade, majoring in Molecular Biology and Physiology, with an average grade of 9.59. She earned her Master's degree in Genomics at the same faculty in 2023 by defending her thesis titled "Polymerase chain reaction as an enrichment method for analysis of DMPK expansions in patients with congenital form of myotonic dystrophy type 1" achieving an average grade of 10.00. The experimental part of her master's thesis was completed at the Human Molecular Genetics, Faculty of Biology, University of Belgrade.

In October of 2024, she enrolled in the Ph.D. program of Animal and Human Physiology and obtained the title of Junior Research Assistant.

As of February 1, 2025, she has been employed at the Department of Neurophysiology, where she will complete her doctoral dissertation.

Throughout her scientific career and professional development, Marija has chosen to focus on the molecular and cellular mechanisms underlying neurodegenerative and malignant diseases, as well as the investigation of novel therapeutics for these conditions using the latest biochemical and molecular methods. Her research will be dedicated to uncovering the roles and regulatory mechanisms of autophagy, oxidative stress, mitochondria, and cell death as potential therapeutic targets.

Understanding the physiological and functional characteristics of cancer cells at the individual level, and the tumor tissue as a highly orchestrated multicellular formation, by whose activity the tumor expands, invades and disseminates, is the main goal of cancer biology research today. Defining the causes of abnormal behavior of neoplastic cells individually and in the context of the tumor microenvironment, including the histological, metabolic and immunological specificities of this tissue, represents a platform for designing new approaches in cancer treatment. Investigating the phenomenon of initial or acquired tumor resistance helps to gain deeper insights into the reasons for limited effects of the conventional treatments, enabling the improvement of existing protocols.

Neurobiology studies the anatomy, physiology, and pathology of the nervous system. From the molecular and biochemical basis of this system, to the study of behavioral plasticity, to understanding the driving forces of neurodegenerative diseases and how they can be treated. Electrophysiology studies biophysical properties in vertebrate neurons and links morphofunctional features of the brain to observed animal behavior. The ultimate goal is to identify active substances that may have a protective effect in neurological and psychiatric diseases.

Wednesday, 19 February 2025 15:11

Zorana Milosavljević

EDUCATION:
2024 – PhD studies, Faculty of Biology, Molecular Biology program, Animal and Human Physiology module
2023 – 2024 – Master of Biology, Biology program, Experimental Biomedicine, Faculty of Biology, University of Belgrade
Master's thesis: "Effects of Glyphosate-Based Herbicides and Elevated Temperature on Oxidative Stress Parameters in Larvae of the Tailed Amphibian Triturus ivanbureschi"
2019 – 2023 – Bachelor of Biochemistry, Faculty of Chemistry, University of Belgrade
Bachelor's thesis: "Biodegradation of Dibenzothiophene by Pseudomonas aeruginosa Strain SAN AI"

WORK EXPERIENCE:
2024 – Research Trainee at the Institute for Biological Research "Siniša Stanković", Department of Immunology
2022 – 2023 – Internship at the Institute of Chemistry, Technology, and Metallurgy

SCIENTIFIC RESEARCH FIELD:
Neuroimmunology, autoimmune diseases, with a focus on multiple sclerosis and the animal model of experimental autoimmune encephalomyelitis. The role of the lung and gut immune system in the pathogenesis of autoimmune diseases.

Inflammation is a response to damage and danger in organisms and is an integral part of research in immunology, but also in other scientific disciplines, since inflammation occurs in numerous pathological conditions like diabetes or cancer. Immunology studies body’s defence mechanisms at cellular and molecular level in infective diseases, as well as immune system malfunctions in autoimmune diseases and allergies Modification of body’s immune system is useful in treatment of these diseases, and can be performed through pharmacological modulation or immunotherapy, where immune cells or their parts are used. Acute-phase proteins and potential biological markers of inflammation involved in the modification and integration of signalling pathways are being investigated in order to predict and intervene in diseases.

Neurobiology studies the anatomy, physiology, and pathology of the nervous system. From the molecular and biochemical basis of this system, to the study of behavioral plasticity, to understanding the driving forces of neurodegenerative diseases and how they can be treated. Electrophysiology studies biophysical properties in vertebrate neurons and links morphofunctional features of the brain to observed animal behavior. The ultimate goal is to identify active substances that may have a protective effect in neurological and psychiatric diseases.

Tuesday, 18 February 2025 13:36

Maja Vukobratović

EDUCATION:
2024 -
PhD in Cellular and Molecular Oncology, Faculty of Biology, University of Belgrade
2023-2024
Master of Science in Cell and Tissue Biology, Faculty of Biology, University of Belgrade
Master’s Thesis: “Structural and redox reprogramming of brown adipose tissue in mice with functionally silenced Nrf2 in an orthotopic breast cancer model”
grade: 10.00
2019-2023
Bachelor's degree in Molecular Biology and Physiology, Faculty of Biology, University of Belgrade
grade: 9.86

WORK EXPERIENCE:

2025 - Junior Research Assistant, Department of Physiology, IBISS, University of Belgrade

RESEARCH INTERESTS:

Molecular mechanisms of redox regulation of vital cellular processes in physiological and pathophysiological conditions such as tumors. The central interest is the investigation of redox-sensitive transcription factors and molecular processes, especially in terms of the potential modulation of cellular redox status for therapeutic purposes.

AWARDS:

2025. “Ivan Đaja” Award for the best master’s thesis in the field of physiology.

Understanding the physiological and functional characteristics of cancer cells at the individual level, and the tumor tissue as a highly orchestrated multicellular formation, by whose activity the tumor expands, invades and disseminates, is the main goal of cancer biology research today. Defining the causes of abnormal behavior of neoplastic cells individually and in the context of the tumor microenvironment, including the histological, metabolic and immunological specificities of this tissue, represents a platform for designing new approaches in cancer treatment. Investigating the phenomenon of initial or acquired tumor resistance helps to gain deeper insights into the reasons for limited effects of the conventional treatments, enabling the improvement of existing protocols.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Lecturer: Dr. Slobodan Davidović, Department of Population Genetics and Ecogenotoxicology, Institute for Biological Research "Siniša Stanković" - National Institute of the Republic of Serbia, University of Belgrade

Time: Wednesday, 26th February 2025, 13.00

Venue: IBISS Library

Understanding the physiological and functional characteristics of cancer cells at the individual level, and the tumor tissue as a highly orchestrated multicellular formation, by whose activity the tumor expands, invades and disseminates, is the main goal of cancer biology research today. Defining the causes of abnormal behavior of neoplastic cells individually and in the context of the tumor microenvironment, including the histological, metabolic and immunological specificities of this tissue, represents a platform for designing new approaches in cancer treatment. Investigating the phenomenon of initial or acquired tumor resistance helps to gain deeper insights into the reasons for limited effects of the conventional treatments, enabling the improvement of existing protocols.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

It is a pleasure for the STRIMHealth team from the University of Belgrade – Institute for Biological Research “Siniša Stanković” (IBISS) to announce the 2nd Training on Targeted and Non-targeted MS-data Analysis in Lipidomics that will be hosted at IBISS (Belgrade, Serbia) from March 11 – 12, 2025.

Understanding the physiological and functional characteristics of cancer cells at the individual level, and the tumor tissue as a highly orchestrated multicellular formation, by whose activity the tumor expands, invades and disseminates, is the main goal of cancer biology research today. Defining the causes of abnormal behavior of neoplastic cells individually and in the context of the tumor microenvironment, including the histological, metabolic and immunological specificities of this tissue, represents a platform for designing new approaches in cancer treatment. Investigating the phenomenon of initial or acquired tumor resistance helps to gain deeper insights into the reasons for limited effects of the conventional treatments, enabling the improvement of existing protocols.

Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

Friday, 14 February 2025 12:11

Tamara Grdović

Education:
PhD studies: University of Belgrade - Faculty of Biology (Belgrade, Serbia), Study program Molecular biology, module Physiology, submodule Animal and Human Physiology, 2024 -
MSc studies in Ecology: University of Belgrade - Faculty of Biology, 2020-2022.
BSc studies in Biology: University of Belgrade - Faculty of Biology, 2015-2020.

Research interests:
Scientific research includes molecular physiological biomonitoring based on the parameters of the antioxidant defense system; general and biomedical ecophysiology.

Employment:
2025 - : Junior Research Assistant, Department of Physiology, Institute for Biological Research “Siniša Stanković” – National Institute of the Republic of Serbia, University of Belgrade.

Ecophysiology studies the physiological processes in living beings that are a response to changes in the external environment and that are fundamental to understanding the mechanisms and interactions that underlie the adaptive strategies of organisms. The effect of climate change, the presence of various pollutants, the availability of nutrients, and habitat degradation are some of those influences that are studied.

Ecotoxicology studeies the toxic effects of chemicals on the environment. The effects are studied at the level of molecules, cells, tissues, organs, individual organisms, populations or ecosystems.

Animal physiology studies how biological processes work, how they operate under different environmental conditions, and how these processes are regulated and integrated. They can be studied at different levels of organisation, from organelles and cell membranes to cells, tissues, organ systems, and the whole animal, both during development and in adulthood.

Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.

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