Isidora Marković is a PhD student at the Faculty of Biology, University of Belgrade. Since February 2025, she has been employed as a junior research assistant at the Department of Molecular Biology of the Institute for Biological Research "Siniša Stanković" - National Institute of the Republic of Serbia. In the same department, she completed her master's thesis entitled "Effect of hydrogen sulfide donors on liver and pancreas of diabetic mice" under the mentorship of dr Ana Stančić and dr Iva Lakić. She is currently researching the effects of different natural and synthetic hydrogen sulfide donors on the regulation of ferroptosis in the pathogenesis of type 1 diabetes, with a focus on enzymes involved in antioxidant defense and iron metabolism. In previous research, she used an in vivo model, specifically the C57BL/6 and NOD mouse strains.
EDUCATION:
2024. – PhD student, Biology of Cells and Tissues module, Faculty of Biology, University of Belgrade;
2024. –MSc in biology, Experimental Biomedicine module, Faculty of Biology, University of Belgrade;
2023. – BSc in biology, Biology module, Faculty of Biology, University of Belgrade;
Animal physiology studies how biological processes work, how they operate under different environmental conditions, and how these processes are regulated and integrated. They can be studied at different levels of organisation, from organelles and cell membranes to cells, tissues, organ systems, and the whole animal, both during development and in adulthood.
Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.
Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.
Understanding the physiological and functional characteristics of cancer cells at the individual level, and the tumor tissue as a highly orchestrated multicellular formation, by whose activity the tumor expands, invades and disseminates, is the main goal of cancer biology research today. Defining the causes of abnormal behavior of neoplastic cells individually and in the context of the tumor microenvironment, including the histological, metabolic and immunological specificities of this tissue, represents a platform for designing new approaches in cancer treatment. Investigating the phenomenon of initial or acquired tumor resistance helps to gain deeper insights into the reasons for limited effects of the conventional treatments, enabling the improvement of existing protocols.
Metabolism is the totality of all chemical reactions that provide energy to cells and maintain the vital state of cells and organisms. Metabolism is a tightly regulated process, and control of metabolic pathways allows organisms to successfully interact with their environment. Metabolic regulation is key to understanding and treating a number of chronic diseases, including diabetes, obesity, hypertension, and cancer.
Redox biology is the study of all aspects of biology mediated or influenced by biochemical processes involving reduction (gain of electrons) and oxidation (loss of electrons). Redox homeostasis is central to the basic functions of life, including metabolism and respiration, and when altered it can promote the progression of disease and ageing.
Dr. Irena Todorović was born on April 27th, 1995 in Belgrade. She graduated from Zemun High School in 2014, after which she enrolled in Undergraduate studies at the Faculty of Biology, University of Belgrade, study program Biology (Ecology module). In 2017, she was the coordinator of the Congress of Biology Students "Simplast". She graduated in 2018, earning the title of Graduated biologist. In the same year, she enrolled in the Master's Program at the Faculty of Agriculture, University of Belgrade, study program Food Technology (module Microbiology of Food and the Environment), and completed them in 2019. She worked on the Master's thesis titled "Possibilities for application of Bacillus megaterium inoculum and Aspergillus piperis metabolites in seed biopriming" at the Department for Environmental Microbiology, and she defended it on July 4th, 2019 with a grade 10, earning the title Master engineer of technology. In the same year, she was awarded a scholarship by the French government for joint Doctoral academic studies at the University Claude Bernard Lyon 1 (Claude Bernard Lyon 1, doctoral school Évolution, Écosystèmes, Microbiologie, Modélisation) and at the University of Belgrade (Faculty of Agriculture, study program Agricultural Sciences), as well as Scholarship from the Foundation for Young Talents in the Republic of Serbia, for the best students studying abroad. On May 31st, 2024, she defended her doctoral dissertation entitled "Indigenous bacterial populations in soil suppressiveness to Fusarium graminearum", earning the title of Doctor of Biotechnical Sciences (in Serbia) and Doctor of the University of Lyon (in France). Dr. Irena Todorović participated in the SupressSoil project, funded by the BiodivERsA3 ERA-Net COFUND program, and the ANR (French National Research Agency), that aimed to understand molecular and ecological processes in soils suppressive to pathogenic fungi, in Germany, Switzerland, Serbia and France. In addition, she participated in the Multilateral Scientific and Technological Cooperation project, which brought together researchers from France, Serbia and the Czech Republic, and aimed to test the suppressiveness of soils to Fusarium graminearum. Irena Todorović speaks, reads and writes English (level C2/C2) and French (level B2/C2).
Biodiversity is the variety and variability of life on Earth. It encompasses diversity at the genetic, taxonomic and ecosystem levels. Biodiversity is important in both natural and artificial ecosystems. Today, biodiversity is threatened by habitat loss and fragmentation, unsustainable resource use, invasive species, pollution and global climate change.
Biotechnology is defined as the use of biological processes and systems (living organisms or their parts) to develop or modify different processes or products useful to humans and includes analysis of risks of its implementation (biosafety).
Mycology is the study of fungi that investigate their genetics, growth, structure, and interactions with other organisms in an ecosystem. The areas of mycological research at the Institute include medicinal mycology, phytopathology, description of new species and their potential application in biotechnology and industry.
Microbiology studies the structure, function, genetics, and ecology of microorganisms, including bacteria, viruses, fungi, and protozoa. Within the Institute, important areas of microbiological research include medical microbiology, environmental microbiology and industrial microbiology.
Environmental protection comprises reduction or prevention of pollution, negative impacts on the environment, damage caused to ecosystems or natural resources caused by human activities.
The work of Ana Stepanović and colleagues was selected in the competition of the "Akademik Radoslav K. Anđus" Foundation for the best scientific publication by a young scientist in the field of physiology/biophysics for 2023/2024: Novel hybrid compounds of sclareol and doxorubicin as potential anticancer nanotherapy for glioblastoma, Biomedicine & Pharmacotherapy 174, 2024, 116496.
Biodiversity is the variety and variability of life on Earth. It encompasses diversity at the genetic, taxonomic and ecosystem levels. Biodiversity is important in both natural and artificial ecosystems. Today, biodiversity is threatened by habitat loss and fragmentation, unsustainable resource use, invasive species, pollution and global climate change.
Biotechnology is defined as the use of biological processes and systems (living organisms or their parts) to develop or modify different processes or products useful to humans and includes analysis of risks of its implementation (biosafety).
Mycology is the study of fungi that investigate their genetics, growth, structure, and interactions with other organisms in an ecosystem. The areas of mycological research at the Institute include medicinal mycology, phytopathology, description of new species and their potential application in biotechnology and industry.
Microbiology studies the structure, function, genetics, and ecology of microorganisms, including bacteria, viruses, fungi, and protozoa. Within the Institute, important areas of microbiological research include medical microbiology, environmental microbiology and industrial microbiology.
Environmental protection comprises reduction or prevention of pollution, negative impacts on the environment, damage caused to ecosystems or natural resources caused by human activities.
Biodiversity is the variety and variability of life on Earth. It encompasses diversity at the genetic, taxonomic and ecosystem levels. Biodiversity is important in both natural and artificial ecosystems. Today, biodiversity is threatened by habitat loss and fragmentation, unsustainable resource use, invasive species, pollution and global climate change.
Biotechnology is defined as the use of biological processes and systems (living organisms or their parts) to develop or modify different processes or products useful to humans and includes analysis of risks of its implementation (biosafety).
Mycology is the study of fungi that investigate their genetics, growth, structure, and interactions with other organisms in an ecosystem. The areas of mycological research at the Institute include medicinal mycology, phytopathology, description of new species and their potential application in biotechnology and industry.
Microbiology studies the structure, function, genetics, and ecology of microorganisms, including bacteria, viruses, fungi, and protozoa. Within the Institute, important areas of microbiological research include medical microbiology, environmental microbiology and industrial microbiology.
Environmental protection comprises reduction or prevention of pollution, negative impacts on the environment, damage caused to ecosystems or natural resources caused by human activities.
Biodiversity is the variety and variability of life on Earth. It encompasses diversity at the genetic, taxonomic and ecosystem levels. Biodiversity is important in both natural and artificial ecosystems. Today, biodiversity is threatened by habitat loss and fragmentation, unsustainable resource use, invasive species, pollution and global climate change.
Biotechnology is defined as the use of biological processes and systems (living organisms or their parts) to develop or modify different processes or products useful to humans and includes analysis of risks of its implementation (biosafety).
Mycology is the study of fungi that investigate their genetics, growth, structure, and interactions with other organisms in an ecosystem. The areas of mycological research at the Institute include medicinal mycology, phytopathology, description of new species and their potential application in biotechnology and industry.
Microbiology studies the structure, function, genetics, and ecology of microorganisms, including bacteria, viruses, fungi, and protozoa. Within the Institute, important areas of microbiological research include medical microbiology, environmental microbiology and industrial microbiology.
Environmental protection comprises reduction or prevention of pollution, negative impacts on the environment, damage caused to ecosystems or natural resources caused by human activities.
Biodiversity is the variety and variability of life on Earth. It encompasses diversity at the genetic, taxonomic and ecosystem levels. Biodiversity is important in both natural and artificial ecosystems. Today, biodiversity is threatened by habitat loss and fragmentation, unsustainable resource use, invasive species, pollution and global climate change.
Biotechnology is defined as the use of biological processes and systems (living organisms or their parts) to develop or modify different processes or products useful to humans and includes analysis of risks of its implementation (biosafety).
Mycology is the study of fungi that investigate their genetics, growth, structure, and interactions with other organisms in an ecosystem. The areas of mycological research at the Institute include medicinal mycology, phytopathology, description of new species and their potential application in biotechnology and industry.
Microbiology studies the structure, function, genetics, and ecology of microorganisms, including bacteria, viruses, fungi, and protozoa. Within the Institute, important areas of microbiological research include medical microbiology, environmental microbiology and industrial microbiology.
Environmental protection comprises reduction or prevention of pollution, negative impacts on the environment, damage caused to ecosystems or natural resources caused by human activities.
Biodiversity is the variety and variability of life on Earth. It encompasses diversity at the genetic, taxonomic and ecosystem levels. Biodiversity is important in both natural and artificial ecosystems. Today, biodiversity is threatened by habitat loss and fragmentation, unsustainable resource use, invasive species, pollution and global climate change.
Biotechnology is defined as the use of biological processes and systems (living organisms or their parts) to develop or modify different processes or products useful to humans and includes analysis of risks of its implementation (biosafety).
Mycology is the study of fungi that investigate their genetics, growth, structure, and interactions with other organisms in an ecosystem. The areas of mycological research at the Institute include medicinal mycology, phytopathology, description of new species and their potential application in biotechnology and industry.
Microbiology studies the structure, function, genetics, and ecology of microorganisms, including bacteria, viruses, fungi, and protozoa. Within the Institute, important areas of microbiological research include medical microbiology, environmental microbiology and industrial microbiology.
Environmental protection comprises reduction or prevention of pollution, negative impacts on the environment, damage caused to ecosystems or natural resources caused by human activities.
The collaborative UTRL project entitled "Probiotic bacteria for the treatment of liver steatosis" aims to develop, validate and commercialise a probiotic product for the purification of fatty liver. The project will be implemented over the next 12 months through a synergistic collaboration between science and industry and involves the Institute for Biological Research "Siniša Stanković" (IBISS), the Institute of Molecular Genetics and Genetic Engineering (IMGGI) and the pharmaceutical company Phytonet.
Biodiversity is the variety and variability of life on Earth. It encompasses diversity at the genetic, taxonomic and ecosystem levels. Biodiversity is important in both natural and artificial ecosystems. Today, biodiversity is threatened by habitat loss and fragmentation, unsustainable resource use, invasive species, pollution and global climate change.
Biotechnology is defined as the use of biological processes and systems (living organisms or their parts) to develop or modify different processes or products useful to humans and includes analysis of risks of its implementation (biosafety).
Mycology is the study of fungi that investigate their genetics, growth, structure, and interactions with other organisms in an ecosystem. The areas of mycological research at the Institute include medicinal mycology, phytopathology, description of new species and their potential application in biotechnology and industry.
Microbiology studies the structure, function, genetics, and ecology of microorganisms, including bacteria, viruses, fungi, and protozoa. Within the Institute, important areas of microbiological research include medical microbiology, environmental microbiology and industrial microbiology.
Environmental protection comprises reduction or prevention of pollution, negative impacts on the environment, damage caused to ecosystems or natural resources caused by human activities.
Biodiversity is the variety and variability of life on Earth. It encompasses diversity at the genetic, taxonomic and ecosystem levels. Biodiversity is important in both natural and artificial ecosystems. Today, biodiversity is threatened by habitat loss and fragmentation, unsustainable resource use, invasive species, pollution and global climate change.
Biotechnology is defined as the use of biological processes and systems (living organisms or their parts) to develop or modify different processes or products useful to humans and includes analysis of risks of its implementation (biosafety).
Mycology is the study of fungi that investigate their genetics, growth, structure, and interactions with other organisms in an ecosystem. The areas of mycological research at the Institute include medicinal mycology, phytopathology, description of new species and their potential application in biotechnology and industry.
Microbiology studies the structure, function, genetics, and ecology of microorganisms, including bacteria, viruses, fungi, and protozoa. Within the Institute, important areas of microbiological research include medical microbiology, environmental microbiology and industrial microbiology.
Environmental protection comprises reduction or prevention of pollution, negative impacts on the environment, damage caused to ecosystems or natural resources caused by human activities.
Phone: +381 11 20 78 300
Fax: +381 11 27 61 433
Email: ibiss@ibiss.bg.ac.rs
Bulevar despota Stefana 142
11108 Belgrade
Serbia
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