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Institute for Biological Research "Siniša Stanković"
National Institute of the Republic of Serbia
University of Belgrade

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SBA-15 nanostructures enable tumor-selective delivery of Ph4Sn with enhanced anticancer activity in melanoma models

Alkylarylorganotin compounds, PhnHex4–nSn (n = 0–4), were prepared, characterized and immobilized into mesoporous nanostructured silica SBA-15. SBA-15 loaded with Ph4Sn (SBA-15|Ph4Sn) showed markedly enhanced antiproliferative activity against B16 and A375 melanoma cells with a >50-fold increase in potency in comparison to its organotin counterpart, demonstrating that SBA-15 significantly enhances the antitumor activity of Ph4Sn. Moreover, SBA-15 increased selectivity...

Effects of sourdough- or regular-bread fermentation, and phytate reduction on iron bioavailability, absorption, and iron status...

This systematic review, conducted under the COST Action CA20218 "Promoting Innovation of fermented foods" (PIMENTO), aimed to evaluate whether sourdough- and regular-bread fermentation improve iron bioavailability, absorption, and status in humans. Screening of PubMed, Scopus, and Cochrane Library (January 1970-December 2024) identified 8 human intervention studies, in healthy or iron-deficient participants, that met inclusion criteria. EFSA's scientific guidance for health claim...

Relationship Between CASA Sperm Motility Parameters and Oxidative-Stress-Related Protein Markers in Common Carp (Cyprinus carpio)

The assessment of sperm quality is essential for improving reproductive efficiency in aquaculture species such as common carp (Cyprinus carpio). While sperm motility is widely used as a key functional indicator, the predictive value of oxidative protein markers for sperm performance remains unclear. In this study, sperm motility and kinematic parameters were assessed using computer-assisted sperm analysis (CASA). Markers of oxidative status, advanced oxidation protein...

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