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Institute for Biological Research "Siniša Stanković"
National Institute of the Republic of Serbia
University of Belgrade

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Variation in Brown Rot Susceptibility and Phenolic Profile at Different Stages of Plum Fruit (Prunus domestica L.) Development

Plum production is severely affected by brown rot caused by Monilinia spp. In this study, the relationship between the content of major phenolic compounds and the severity of brown rot in artificially inoculated fruits of two plum cultivars (“Stanley” and “Čačanska Rodna”) was investigated at three fruit developmental stages. The results showed that the phenolic profiles of healthy fruits did not differ significantly between cultivars. In the early stages of brown rot development...

PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation

Introduction: Platinum-based chemopotentiation by poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) has been confirmed in some non-small-cell lung carcinoma (NSCLC) models, but the molecular mechanisms of PARPi synergy with chemotherapeutics remain poorly clarified. This study aimed to evaluate the efficacy of PARPi niraparib in mitigating resistance to cisplatin through increased ten-eleven translocation (TET) enzymatic activity and 5-hydroxymethylcytosine (5hmC) level in human...

The Application of Recycled Jute Non-woven Material Loaded with Zinc Ions as Substrates for Plant Growth

The challenges posed by polluted effluents containing heavy metal ions and the increasing amounts of textile waste necessitate prompt action. In response to these environmental concerns, a non-woven sorbent made from jute fibers, recycled from the carpet industry, has been developed. To enhance the sorption capacity for Zn2+ ions, the jute fibers were modified with the biopolymer alginate. The successful application of the alginate coating on the jute...

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